Luteinizing hormone-choriogonadotropin receptor (LHCGR), a class A G protein-coupled receptor (GPCR), plays a pivotal role in the maturation of reproductive organs and embryonic development.Compared with other GPCRs, the subfamily of LHCGR has a large extracellular domain (ECD) to interact with glycoprotein hormones.A unique hinge region connects t
Hepatitis C virus (HCV) is a global health issue.Although direct-acting antivirals are available to target HCV, there is currently no vaccine.The diversity of the virus is a major obstacle to HCV vaccine development.One approach toward a vaccine is to utilize a strategy to elicit broadly neutralizing antibodies (bNAbs) that target highly-conserved
Abstract Introduction Cutaneous malignant melanomas rarely occur in the eye, usually in the eyelids or the conjunctiva.Conjunctival malignant melanomas are even rarer.Most melanomas are dark in color as they are pigmented.However, Bun Pans amelanotic conjunctival malignant melanomas, a scarce variant of the cancer, can be challenging to diagnose ac
Ex situ seed banking is a practical and cost-effective means Bumper Plates of preserving wild plant diversity and a crucial complement to the in situ conservation and restoration of species and habitats.As pressures on the natural environment have grown, so has the call for seed banks to provide scientifically-robust, practical solutions to seed-re
Introduction Vertigo, dizziness and balance problems (VDB) as well as osteoarthritis (OA) are among the health conditions with the greatest impact on mobility and social participation in older adults.Patients with VDB and OA were shown to benefit from specialised care such as vestibular rehabilitation therapy or joint replacement.However, these eff